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Sirtuins inhibitor AK-7, Purity ≥98%
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Cat. No.: X24-05-ZQ338

Sirtuins inhibitor AK-7, Purity ≥98%

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Synonym: 420831-40-9; AK7; Sirtuins inhibitor

  • CAS Number: 420831-40-9
  • Compound CID: 1328033
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AK-7, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT2.
Molecular Weight
437.35
Molecular Formula
C19H21BrN2O3S
Targets
SIRT2: 15.5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 77 mg/mL (176.06 mM); Water: Insoluble; Ethanol: 3 mg/mL (6.85 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AK-7 is applied to study the role of SIRT2 in Huntington's disease models by inhibiting its activity.
Publications
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