Cambinol, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1 and SIRT2.
Cambinol is used to examine the role of SIRT1 and SIRT2 in cancer and aging by inhibiting these enzymes.
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