Camptothecin, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase. It targets the Topo I (cell-free assay).
Molecular Weight
348.4
Molecular Formula
C20H16N2O4
Targets
Topo I (Cell-free assay): 0.68 μM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Camptothecin is a DNA damage inhibitor that displays the significant potential to act as an effective starting point for developing derivatives like irinotecan and topotecan.
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