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Topoisomerase inhibitor, Irinotecan HCl trihydrate, Purity ≥98%
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Cat. No.: X24-08-YM019

Topoisomerase inhibitor, Irinotecan HCl trihydrate, Purity ≥98%

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Synonym: 136572-09-3; CPT 11; Camptosar; Campto; Irinotecan; [(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate; trihydrate; hydrochloride

  • MDL: MFCD01862255
  • CAS Number: 136572-09-3
  • Compound CID: 60837
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Product Size
200 mg; 500 mg; 1 g; 2 g
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Irinotecan HCl trihydrate, soluble in DMSO, water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.
Molecular Weight
677.2
Molecular Formula
C33H38N4O6·HCl·3H2O
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 92 mg/mL (135.86 mM); Water: 1 mg/mL (1.47 mM); Ethanol: 6 mg/mL (8.85 mM)
Applications
Irinotecan HCl trihydrate is a DNA damage inhibitor that plays a key role in inhibiting topoisomerase I, thereby interfering with DNA replication and promoting cancer cell death.
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