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Topoisomerase inhibitor, Dxd, Purity ≥98%
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Cat. No.: X24-08-YM068

Topoisomerase inhibitor, Dxd, Purity ≥98%

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Synonym: 1599440-33-1; Exatecan derivative for ADC; N-[(10S,23S)-10-Ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide

  • CAS Number: 1599440-33-1
  • Compound CID: 117888634
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Product Size
1 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Dxd is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase. It targets the topoisomerase I.
Molecular Weight
493.48
Molecular Formula
C26H24FN3O6
Targets
Topoisomerase I: 0.31 μM (IC50)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Applications
Dxd is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of HER2-positive cancers, including breast cancer and gastric cancer.
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