Mitoxantrone hydrochloride, soluble in DMSO and water and insoluble in ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.
Molecular Weight
517.4
Molecular Formula
C22H28N4O6·2HCl
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 79 mg/mL (152.68 mM); Water: 79 mg/mL (152.68 mM); Ethanol: insoluble; In vivo: Saline, 28 mg/mL
Applications
Mitoxantrone hydrochloride is a DNA damage inhibitor that plays a key role in managing multiple sclerosis due to its immunosuppressive effects.
Publications
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Publications
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