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12-O-Tetradecanoyl phorbol-13-acetate
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Cat. No.: X23-12-YM025

12-O-Tetradecanoyl phorbol-13-acetate

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Synonym: 16561-29-8; TPA; Phorbol 12-myristate 13-acetate

  • CAS Number: 16561-29-8
  • PubChem CID: 27924
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
12-O-Tetradecanoyl phorbol-13-acetate, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets NF-κB, and PKC.
Molecular Weight
616.83
Molecular Formula
C36H56O8
Targets
NF-κB; PKC: 11.7 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 94 mg/mL (152.38 mM); Water: insoluble; Ethanol: 94 mg/mL
Applications
12-O-Tetradecanoyl phorbol-13-acetate can be used to help develop potential therapeutic strategies for certain diseases, such as inflammatory disease, fibrotic diseases, and cancer.
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