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GF 109203X
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Cat. No.: X23-12-YM010

GF 109203X

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Synonym: 133052-90-1; GF-109203X; GF109203X; GO6850; GO-6850; Bisindolylmaleimide I

  • CAS Number: 133052-90-1
  • PubChem CID: 2396
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GF 109203X, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PKCα, PKCβ1, EGFR, insulin receptor, PDGFR, PKCβ2, and PKCγ.
Molecular Weight
412.49
Molecular Formula
C25H24N4O2
Targets
PKCα: 20 nM; PKCβ1: 17 nM; EGFR: >100 μM; Insulin receptor: >100 μM; PDGFR: 65 μM; PKCβ2: 16 nM; PKCγ: 20 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 70 mg/mL (169.7 mM); Water: insoluble; Ethanol: insoluble
Applications
GF 109203X can be used as a lead compound in the development of pharmacological agents targeting PKC inhibition.
Publications
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