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Bcr-Abl inhibitor AMN-107, Purity ≥98%

Cat. No.: X24-06-ZQ483

Bcr-Abl inhibitor AMN-107, Purity ≥98%

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Synonym: 641571-10-0; Bcr-Abl inhibitor; AMN107

  • MDL: MFCD09833716
  • CAS Number: 641571-10-0
  • Compound CID: 644241
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Product Size
100 mg; 200 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AMN-107, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl (Murine myeloid progenitor cells).
Molecular Weight
529.5
Molecular Formula
C28H22F3N7O
Targets
Bcr-Abl (Murine myeloid progenitor cells): <30 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 26 mg/mL (49.09 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMN-107 inhibits Bcr-Abl, focusing on treating drug-resistant chronic myeloid leukemia.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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