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Bcr-Abl inhibitor Dasatinib monohydrate, Purity ≥98%
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Cat. No.: X24-06-ZQ367

Bcr-Abl inhibitor Dasatinib monohydrate, Purity ≥98%

Synonym: 863127-77-9; Bcr-Abl inhibitor; BMS354825

  • MDL: MFCD08704581
  • CAS Number: 863127-77-9
  • Compound CID: 11540687
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Product Size
500 mg; 1 g; 2 g; 5 g
Price
Datasheet
MSDS
Properties
Description
Dasatinib monohydrate specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl, c-Kit, FGFR1, Her1, Her2, lck, MEK, p38, PDGFRβ, and Src.
Molecular Weight
506.02
Molecular Formula
C22H28ClN7O3S
Targets
Bcr-Abl: 1.0 nM; c-Kit: 5.0 nM; FGFR1: 880 nM; Her1: 180 nM; Her2: 710 nM; lck: 0.4 nM; MEK: 1700 nM; p38: 100 nM; PDGFRβ: 28 nM; Src: 0.5 nM; yes: 0.5 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Dasatinib monohydrate is examined in lab settings to inhibit Bcr-Abl and Src family kinases, offering insights for chronic myeloid leukemia treatment.
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