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Bcr-Abl inhibitor GNF 7, Purity ≥98%

Cat. No.: X24-06-ZQ462

Bcr-Abl inhibitor GNF 7, Purity ≥98%

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Synonym: 839706-07-9; Bcr-Abl inhibitor; GNF7; GNF 7

  • MDL: MFCD18251569
  • CAS Number: 839706-07-9
  • Compound CID: 11478363
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GNF 7, soluble in warmed DMSO and insoluble in water and ethanol, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets c-Abl, E255V, G250E, M351T, and T315I.
Molecular Weight
547.53
Molecular Formula
C28H24F3N7O2
Targets
c-Abl: 133 nM; E255V: 122 nM; G250E: 136 nM; M351T: <5 nM; T315I: 61 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 17 mg/mL (40.63 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNF 7 acts on Bcr-Abl to study its application in hematological malignancies.
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