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BTK inhibitor PCI-32765, Purity ≥98%
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Cat. No.: X24-06-ZQ495

BTK inhibitor PCI-32765, Purity ≥98%

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Synonym: 936563-96-1; BTK inhibitor; Ibrutinib

  • MDL: MFCD20261150
  • CAS Number: 936563-96-1
  • Compound CID: 24821094
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Product Size
10 mg; 25 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PCI-32765, soluble in DMSO and ethanol and insoluble in water, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells. It targets BLK, BMX, Abl, BRK, BTK, c-Src, CSK, EGFR, ErbB2, FER, and FGR.
Molecular Weight
440.5
Molecular Formula
C25H24N6O2
Targets
BLK: 0.5 nM; BMX: 0.8 nM; Abl: 86 nM; BRK: 3.3 nM; BTK: 0.5 nM; c-Src: 171 nM; CSK: 2.3 nM; EGFR: 5.6 nM; ErbB2: 9.4 nM; FER: 8.07 nM; FGR: 2.3 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (183.88 mM); Water: Insoluble; Ethanol: 41 mg/mL (93.07 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PCI-32765 also known as Ibrutinib, is a BTK inhibitor with applications in cancer research.
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