Carbohydrate-based Nanohydrogel Production Service
Characteristics of Nanohydrogel
Nanohydrogel is a hydrogel material with a nanoscale three-dimensional network structure, which combines the advantages of high specific surface area and quantum size effect of nanomaterials with high water content and biocompatibility of hydrogels. This unique structure gives nanohydrogel many excellent properties, such as high drug loading, sustained release performance, good biocompatibility, controllable degradation, etc. With the advanced GlycoNano™ Platform, CD BioGlyco uses advanced technology to provide clients with unparalleled Glycol Nanohydrogel Development Services to meet your diverse needs in scientific research, development, and production. The Technologies we commonly use for the development of glycol nanohydrogels include but are not limited to:
- Precipitation Polymerization
- Inverse Emulsion Polymerization
- Microtemplate-assisted Polymerization
- Precipitation/Crosslinking
- Emulsion/Crosslinking
- Self-assembly/Crosslinking
- Microtemplating/Crosslinking
We use different technologies to provide clients with the following glycol nanohydrogel development services, including but not limited to:
Natural Polymer-based Glycol Nanohydrogel Production
- Carbohydrate
- Glycosaminoglycan
- Polypeptide/Glycoprotein
Synthetic Polymer-based Glycol Nanohydrogel Production
- Polylactic Acid (PLA)
- Polyvinyl Alcohol (PVA)
- Polylactic-co-Glycolic Acid (PLGA)
- Poly (l-lactic Acid) (PLLA)
- Polydioxanone (PDO)
Tailored to Your Needs: Precision Carbohydrate-based Nanohydrogels
Our team provides clients with high-quality, customized carbohydrate-based nanohydrogel production services. We use rigorous scientific methods to ensure the quality of hydrogels through refined processing of raw materials, diverse synthesis strategies, precise functional modification, and comprehensive characterization analysis. Our services are as follows:
Carbohydrate Preparation
To meet the needs of our clients to the greatest extent, we provide flexible and diverse services. Clients provide us with purified carbohydrates so that we directly prepare hydrogels. We also extract and purify carbohydrates from raw materials and finally prepare high-purity carbohydrate nanohydrogels. The customized service ensures that we provide the most optimized solution based on the specific requirements of our clients. We prepare nanohydrogels based on the following carbohydrates:
- Chondroitin
- Pullulan
- Chitosan
- Alginate
- Dextran
- Agarose
- Pectin
- Starch
- Xanthan Gum
- Gellan Gum
- Carrageenan
- Cellulose
- Cyclodextri
Nanohydrogel Synthesis
To meet clients' diverse needs for nanohydrogel performance, we use a variety of hydrogel synthesis technologies, such as free radical polymerization, ionic crosslinking, physical crosslinking, microemulsion polymerization, etc. We finely control reaction conditions such as temperature, pH value, monomer concentration, crosslinker dosage, etc. to prepare nanohydrogels with different network structures, porosities, and mechanical properties.
Characterization
We use scanning electron microscopy (SEM), transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and other technologies to characterize the prepared nanohydrogel. Through comprehensive analysis of the hydrogel's morphology, particle size distribution, chemical composition, thermal stability, etc., we ensure the structure and performance of the prepared nanohydrogel.
Workflow

Applications
- Carbohydrate-based nanohydrogels are used as drug carriers to achieve sustained and controlled release of drugs, targeted delivery, and improve drug stability and bioavailability.
- Carbohydrate-based nanohydrogels are used as cell culture scaffolds with the advantages of good biocompatibility and degradability. Nanohydrogels promote cell growth, proliferation, and differentiation, and are used for tissue repair and regeneration.
- Construct carbohydrate-based nanohydrogels for biosensors to detect biomolecules and small molecule compounds in samples such as blood and urine.
Advantages
- We use commercial carbohydrates or extract and purify high-purity carbohydrates from natural samples to prepare carbohydrate-based nanohydrogels.
- Prepare the optimal synthesis strategy and synthesis route according to the reaction characteristics, control the particle size, porosity, cross-linking density, and other parameters of the hydrogel, and achieve precise regulation of material properties.
- We provide a full range of customized services from raw material development, route design, and process optimization to performance characterization to meet your personalized needs.
Publication Data
DOI: 10.3390/polym15234501
Journal: Polymers
Published: 2023
IF: 4.7
Results: The development of scaffolds for bone regeneration is crucial for the treatment of bone diseases or injuries. The authors developed an injectable hydrogel for bone regeneration based on the natural polymer dextran, and incorporated inorganic compounds β-tricalcium phosphate and nanohydroxyapatite into the hydrogel structure to enhance the mechanical properties of its 3D mesh. Attenuated total reflectance-FTIR (ATR-FTIR) and NMR were used to characterize, and its degradation rate, swelling ability, release and mechanical properties were evaluated. The results showed that the dextran-based hydrogel was successfully synthesized with the drug release curve of 50%~80%, good biocompatibility, and Young's modulus (200-300 kPa), and has the potential to be used in bone regeneration applications.
Fig.1 ATR-FTIR spectra of dextran-based hydrogel. (Alves, et al., 2023)
Frequently Asked Questions
- How do you ensure the purity and quality of nanohydrogel?
We adopt a strict quality control system, from raw material preparation to product delivery, every step is strictly monitored to ensure the purity and quality of the product. -
If I want to customize the product, what information do I need to provide?
You need to contact us to understand the specific application of nanohydrogel (such as drug delivery, tissue engineering, biosensors, cosmetics, etc.), the required properties (particle size, porosity, cross-linking density, degradation rate, surface functional groups, etc.), and size (milligram to kilogram level).
CD BioGlyco helps clients develop biocompatible, degradable, and modifiable carbohydrate-based nanohydrogels for drug delivery, tissue engineering, etc. Please feel free to contact us and we will tailor a solution for you.
Reference
- Alves, P., et al. Dextran-based injectable hydrogel composites for bone regeneration. Polymers. 2023, 15(23): 4501.
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