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CRM1 inhibitor, KPT185, Purity ≥98%
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Cat. No.: X24-09-YM516

CRM1 inhibitor, KPT185, Purity ≥98%

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Synonym: 1333151-73-7; KPT 185; KPT-185; Propan-2-yl (Z)-3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoate; CRM1 inhibitor

  • CAS Number: 1333151-73-7
  • Compound CID: 53495165
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
KPT185, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of membrane transporters-ion channels by inhibiting CRM1. The molecular weight of the compound is 355.31, and its molecular formula is C16H16F3N3O3.
Molecular Weight
355.31
Molecular Formula
C16H16F3N3O3
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 60 mg/mL (168.86 mM); Water: insoluble; Ethanol: 60 mg/mL (168.86 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
KPT185 can be used for its potential in various cancers, particularly those with alterations in nuclear transport mechanisms.
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