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CRM1 inhibitor, Leptomycin B, Purity ≥98%
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Cat. No.: X24-09-YM521

CRM1 inhibitor, Leptomycin B, Purity ≥98%

Synonym: 87081-35-4; CI 940; CI940; CI-940; LMB; (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-Ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid; CRM1 inhibitor

  • MDL: MFCD06795848
  • CAS Number: 87081-35-4
  • Compound CID: 6917907
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Product Size
1 mg; 5 mg; 10 mg; 20 mg
Price
Datasheet
MSDS
Properties
Description
Leptomycin B is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of membrane transporters-ion channels by inhibiting CRM1. The molecular weight of the compound is 540.73, and its molecular formula is C33H48O6.
Molecular Weight
540.73
Molecular Formula
C33H48O6
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Identity
Confirmed by NMR/HPLC/MS.
Applications
Leptomycin B can be used for its anti-cancer properties, particularly in leukemia and solid tumors, by promoting apoptosis and cell cycle arrest.
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