Pemetrexed disodium, insoluble in DMSO and ethanol and soluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting DHFR. The molecular weight of the compound is 471.4, and its molecular formula is C20H19N5Na2O6. It targets the DHFR (Cell-free assay), GARFT (Cell-free assay) and TS (Cell-free assay).
Molecular Weight
471.4
Molecular Formula
C20H19N5Na2O6
Targets
DHFR (Cell-free assay)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: insoluble; Water: 87 mg/mL (184.56 mM); Ethanol: insoluble; In vivo: Saline, 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pemetrexed disodium can be studied extensively for its potential therapeutic applications in the treatment of non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma.
Publications
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Publications
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