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FGFR inhibitor AZD4547, Purity ≥98%
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Cat. No.: X24-06-ZQ071

FGFR inhibitor AZD4547, Purity ≥98%

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Synonym: 1035270-39-3; FGFR inhibitor; AZD-4547

  • MDL: MFCD22580423
  • CAS Number: 1035270-39-3
  • Compound CID: 51039095
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD4547, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR2, FGFR3, Akt1, ALK1, Axl, CDK2, FAK, FGFR1, FGFR4, and IGFR.
Molecular Weight
463.6
Molecular Formula
C26H33N5O3
Targets
FGFR2: 2.5 nM; FGFR3: 1.8 nM; Akt1: >100 μM; ALK1: >100 μM; Axl: >2 μM; CDK2: >10 μM; FAK: >10 μM; FGFR1: 0.2 nM; FGFR4: 165 nM; IGFR: 581 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 79 mg/mL (170.41 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD4547 targets FGFR signaling pathways, crucial in the study of certain aggressive cancers.
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Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Cyclodextrin
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Dextran
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