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FGFR inhibitor BGJ398, Purity ≥98%
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Cat. No.: X24-06-ZQ072

FGFR inhibitor BGJ398, Purity ≥98%

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Synonym: 872511-34-7; FGFR inhibitor; BGJ-398

  • MDL: MFCD22123241
  • CAS Number: 872511-34-7
  • Compound CID: 53235510
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BGJ398, soluble in warmed DMSO and insoluble in water and ethanol, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR2, FGFR3, Abl, FGFR1, FGFR3 (K650E), FGFR4, Fyn, Kit, LCK, Lyn, and VEGFR2.
Molecular Weight
560.48
Molecular Formula
C26H31Cl2N7O3
Targets
FGFR2: 1.4 nM; FGFR3: 1.0 nM; Abl: 2.3 nM; FGFR1: 0.9 nM; FGFR3 (K650E): 4.9 nM; FGFR4: 60 nM; Fyn: 1.9 μM; Kit: 0.75 μM; LCK: 2.5 μM; Lyn: 0.30 μM; VEGFR2: 0.18 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 1 mg/mL (1.78 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
BGJ398 is employed as an FGFR inhibitor, offering avenues for research into targeted cancer therapies.
Publications
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