Cat. No.: X24-06-ZQ078
FGFR inhibitor Debio-1347, Purity ≥98%
Synonym: 1265229-25-1; FGFR inhibitor; Debio 1347; Debio1347; CH5183284; CH 5183284; CH-5183284; FF-284; FF284; FF 284
- MDL: MFCD28502053
- CAS Number: 1265229-25-1
- Compound CID: 66555680
Product Size
5 mg; 10 mg; 25 mg; 50 mg
Properties
Description
Debio-1347, soluble in DMSO and warmed ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.
Molecular Formula
C20H16N6O
Targets
FGFR1: 9.3 nM; FGFR2: 7.6 nM; FGFR3: 22 nM; FGFR4: 290 nM
Solubility
DMSO: 70 mg/mL (196.41 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Debio-1347 is used to investigate and inhibit FGFR, contributing to cancer research, specifically targeting tumors with FGFR genetic alterations.
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