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FGFR inhibitor Futibatinib, Purity ≥98%
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Cat. No.: X24-06-ZQ091

FGFR inhibitor Futibatinib, Purity ≥98%

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Synonym: 1448169-71-8; FGFR inhibitor; TAS-120; TAS120; TAS 120

  • CAS Number: 1448169-71-8
  • Compound CID: 71621331
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Product Size
1 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Futibatinib, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR2 E566G, FGFR2 N550H, FGFR2 V5651, FGFR3, FGFR4, and wild-type FGFR2.
Molecular Weight
418.45
Molecular Formula
C22H22N6O3
Targets
FGFR1: 3.9 nM; FGFR2: 1.3 nM; FGFR2 E566G: 2.4 nM; FGFR2 N550H: 3.6 nM; FGFR2 V5651: 1-3 nM; FGFR3: 1.6 nM; FGFR4: 8.3 nM; wild-type FGFR2: 0.3 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 75 mg/mL (179.23 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Futibatinib is employed in exploring FGFR as a selective inhibitor, aiding in the development of FGFR-targeted cancer therapies.
Publications
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