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FGFR inhibitor JNJ-42756493, Purity ≥98%
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Cat. No.: X24-06-ZQ084

FGFR inhibitor JNJ-42756493, Purity ≥98%

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Synonym: 1346242-81-6; FGFR inhibitor; JNJ 42756493; JNJ42756493; JNJ-42756493

  • MDL: MFCD28502040
  • CAS Number: 1346242-81-6
  • Compound CID: 67462786
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
JNJ-42756493, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, and FGFR4.
Molecular Weight
446.55
Molecular Formula
C25H30N6O2
Targets
FGFR1: 1.2 nM; FGFR2: 2.5 nM; FGFR3: 3.0 nM; FGFR4: 5.7 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 79 mg/mL (176.92 mM); Water: Insoluble; Ethanol: 79 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
JNJ-42756493 is applied in investigating FGFR inhibition in cancer research, specifically for targeting tumors that exhibit FGFR pathway activation.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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