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FGFR inhibitor LY 2874455, Purity ≥98%
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Cat. No.: X24-06-ZQ094

FGFR inhibitor LY 2874455, Purity ≥98%

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Synonym: 1254473-64-7; FGFR inhibitor; LY-2874455; LY2874455

  • CAS Number: 1254473-64-7
  • Compound CID: 46944259
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LY 2874455, soluble in DMSO and warmed ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, FGFR4, and VEGFR2.
Molecular Weight
444.31
Molecular Formula
C21H19Cl2N5O2
Targets
FGFR1: 2.8 nM; FGFR2: 2.6 nM; FGFR3: 6.4 nM; FGFR4: 6 nM; VEGFR2: 7 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (193.55 mM); Water: Insoluble; Warmed ethanol: 56 mg/mL (126.03 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LY 2874455 is applied in FGFR research, serving as a selective inhibitor to help elucidate FGFR’s role in cancer development.
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