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FGFR inhibitor Nintedanib esylate, Purity ≥98%
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Cat. No.: X24-06-ZQ096

FGFR inhibitor Nintedanib esylate, Purity ≥98%

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Synonym: 656247-18-6; FGFR inhibitor; BIBF-1120 esylate

  • MDL: MFCD26142360
  • CAS Number: 656247-18-6
  • Compound CID: 135476717
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Product Size
10 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Nintedanib esylate, soluble in DMSO, water and ethanol, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, FGFR2, FGFR3, PDGFRα, PDGFRβ, VEGFR1, VEGFR2, and VEGFR3.
Molecular Weight
649.76
Molecular Formula
C33H39N5O7S
Targets
FGFR1: 69 nM; FGFR2: 37 nM; FGFR3: 108 nM; PDGFRα: 59 nM; PDGFRβ: 65 nM; VEGFR1: 34 nM; VEGFR2: 13 nM; VEGFR3: 13 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 89 mg/mL (136.97 mM); Water: 89 mg/mL (136.97 mM); Ethanol: 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nintedanib esylate is used to inhibit FGFR in research, contributing to the understanding of FGFR’s involvement in fibrotic and cancerous diseases.
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