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FGFR inhibitor ODM-203, Purity ≥98%
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Cat. No.: X24-06-ZQ099

FGFR inhibitor ODM-203, Purity ≥98%

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Synonym: 1430723-35-5; FGFR inhibitor; ODM203; ODM 203

  • CAS Number: 1430723-35-5
  • Compound CID: 71554322
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ODM-203, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets DDR1, FGFR1, FGFR2, FGFR3, FGFR4, MAP4K4, MINK1, PDGFRα, RET, SIK3, and VEGFR1.
Molecular Weight
505.54
Molecular Formula
C26H21F2N5O2S
Targets
DDR1: 6 nM; FGFR1: 11 nM; FGFR2: 16 nM ; FGFR3: 6 nM; FGFR4: 35 nM; MAP4K4: 49 nM; MINK1: 41 nM; PDGFRα: 35 nM; RET: 8 nM; SIK3: 23 nM; VEGFR1: 26 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (178.02 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ODM-203 serves as a research tool to investigate FGFR inhibition, advancing the understanding of its therapeutic potential in FGFR-driven malignancies.
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O-Glycan
Core 2 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW178) Core 2 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW179) Core 3 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW180) Core 3 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW181) Core 4 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW182) T antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW192) T antigen O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW193) Tn antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW194)
Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
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Cyclodextrin
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Dextran
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