Cat. No.: X24-06-ZQ103
FGFR inhibitor PD173074, Purity ≥98%
Synonym: 219580-11-7; FGFR inhibitor; PD-173074
- MDL: MFCD08705327
- CAS Number: 219580-11-7
- Compound CID: 1401
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
PD173074, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets c-Src, VEGFR2, EGFR, FGFR1, Insulin receptor, MEK, and PKC.
Molecular Formula
C28H41N7O3
Targets
c-Src: 19.8 μM; VEGFR2: 100-200 nM; EGFR: >50 μM; FGFR1: 25 nM; Insulin receptor: >50 μM; MEK: >50 μM; PKC: >50 μM
Solubility
DMSO: 86 mg/mL (164.22 mM); Water: Insoluble; Ethanol: 86 mg/mL (164.22 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD173074 aids in the study of FGFR inhibition in cancer research, targeting FGFR’s role in tumor progression.
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