FGFR inhibitor PRN1371, Purity ≥98%

Synonym: 1802929-43-6; FGFR inhibitor; PRN 1371; PRN-1371

CAS Number: 1802929-43-6
Compound CID: 118295624

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

PRN1371, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets CSF1R, FGFR1, FGFR2, FGFR3, and FGFR4.

Molecular Weight

561.46

Molecular Formula

C₂₆H₃₀Cl₂N₆O₄

Targets

CSF1R: 8.1 nM; FGFR1: 0.6 nM; FGFR2: 1.3 nM; FGFR3: 4.1 nM; FGFR4: 19.3 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 95 mg/mL (169.2 mM); Water: Insoluble; Ethanol: 6 mg/mL (10.68 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PRN1371 serves as a selective FGFR inhibitor in scientific studies, advancing research on FGFR-related cancer biology and treatment strategies.