Cat. No.: X24-06-ZQ106
FGFR inhibitor PRN1371, Purity ≥98%
Synonym: 1802929-43-6; FGFR inhibitor; PRN 1371; PRN-1371
- CAS Number: 1802929-43-6
- Compound CID: 118295624
Product Size
1 mg; 5 mg; 10 mg; 50 mg
Properties
Description
PRN1371, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets CSF1R, FGFR1, FGFR2, FGFR3, and FGFR4.
Molecular Formula
C26H30Cl2N6O4
Targets
CSF1R: 8.1 nM; FGFR1: 0.6 nM; FGFR2: 1.3 nM; FGFR3: 4.1 nM; FGFR4: 19.3 nM
Solubility
DMSO: 95 mg/mL (169.2 mM); Water: Insoluble; Ethanol: 6 mg/mL (10.68 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PRN1371 serves as a selective FGFR inhibitor in scientific studies, advancing research on FGFR-related cancer biology and treatment strategies.
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