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FGFR inhibitor TKI258 dilactic acid, Purity ≥98%
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Cat. No.: X24-06-ZQ081

FGFR inhibitor TKI258 dilactic acid, Purity ≥98%

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Synonym: 852433-84-2; FGFR inhibitor; CHIR-258; TKI258

  • CAS Number: 852433-84-2
  • Compound CID: 135985126
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TKI258 dilactic acid is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets c-Kit, FGFR1, c-Met, CSF-1R/c-Fms, EGFR, EphA2, FGFR3, FLT3, HER2, IGF-1R, and Insulin receptor.
Molecular Weight
572.6
Molecular Formula
C21H21FN6O.2C3H6O3
Targets
c-Kit: 2 nM; FGFR1: 8 nM; c-Met: >3 μM; CSF-1R/c-Fms: 36 nM; EGFR: 2 μM; EphA2: 4 μM; FGFR3: 9 μM; FLT3: 1 μM; HER2: >10 μM; IGF-1R: >10 μM; Insulin receptor: 2 μM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
TKI258 dilactic acid is utilized to study FGFR in the context of its role in cancer, providing a research tool for exploring FGFR-targeted therapies.
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