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FLT3 inhibitor TG-101348, Purity ≥98%
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Cat. No.: X23-10-ZQ422

FLT3 inhibitor TG-101348, Purity ≥98%

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Synonym: Fedratinib; 936091-26-8; Tg-101348; TG101348; SAR302503; SAR-302503; N-(tert-Butyl)-3-((5-methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide; FLT3 inhibitor

  • MDL: MFCD12922515
  • CAS Number: 936091-26-8
  • Compound CID: 16722836
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TG-101348, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FLT3. It targets FLT3, JAK2, JAK2 (V617F), and RET.
Molecular Weight
524.7
Molecular Formula
C27H36N6O3S
Targets
FLT3: 15 nM; JAK2: 3 nM; JAK2 (V617F): 3 nM; RET: 48 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (171.53 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TG-101348 can be employed to study its JAK2 inhibition in myeloproliferative neoplasm research.
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