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Ro 31-8220 mesylate
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Cat. No.: X23-12-YM013

Ro 31-8220 mesylate

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Synonym: 138489-18-6; BIM IX; Bisindolylmaleimide IX (mesylate)

  • CAS Number: 138489-18-6
  • PubChem CID: 11628205
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Ro 31-8220 mesylate, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PKCα, PKCβ1, PKCβ2, PKCε, and PKCγ.
Molecular Weight
553.7
Molecular Formula
C25H23N5O2S·CH3SO3H
Targets
PKCα: 5 nM; PKCβ1: 24 nM; PKCβ2: 14 nM; PKCε: 24 nM; PKCγ: 27 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 85 mg/mL (153.52 mM); Water: insoluble; Ethanol: insoluble
Applications
Ro 31-8220 mesylate can be used to help develop potential therapeutic strategies for certain diseases, such as inflammatory disease, fibrotic diseases, and cancer.
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