Cat. No.: X23-12-YM016
GO6983
Synonym: 133053-19-7; Go-6983; Go 6983
- CAS Number: 133053-19-7
- PubChem CID: 3499
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
GO6983, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PKCα, PKCβ, PKCδ, PKCγ, PKCμ, and PKCζ.
Molecular Formula
C26H26N4O3
Targets
PKCα: 7 nM; PKCβ: 7 nM; PKCδ: 10 nM; PKCγ: 6 nM; PKCμ: 20 μM; PKCζ: 60 nM
Solubility
DMSO: 55 mg/mL (124.29 mM); Water: insoluble; Ethanol: insoluble
Applications
GO6983 can be used to help elucidate the functions of this enzyme in processes such as cell proliferation, differentiation, apoptosis, and neurotransmitter release.
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