Bictegravir, soluble in DMSO and insoluble in ethanol and water, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread.
Bictegravir is utilized in studies involving HIV-1 to investigate its effectiveness as an integrase strand transfer inhibitor, supporting research on reducing viral integration into host DNA.
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