Cat. No.: X24-06-ZQ913
HIV integrase inhibitor S/GSK1349572, Purity ≥98%
Synonym: 1051375-16-6; HIV integrase inhibitor; Dolutegravir; GSK-1349572
- MDL: MFCD20488027
- CAS Number: 1051375-16-6
- Compound CID: 54726191
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
S/GSK1349572, soluble in warmed DMSO and insoluble in water and ethanol, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread. It targets HIV integrase.
Molecular Formula
C20H19F2N3O5
Targets
HIV integrase: 2.7 nM
Solubility
Warmed DMSO: 71 mg/mL (169.3 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
S/GSK1349572 is studied for its action against HIV-1 integrase to block viral DNA integration.
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