GS-9137, soluble in DMSO and ethanol and insoluble in water, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread. It targets HIV-1 IIIB, HIV-2 EHO, and HIV-2 ROD.
GS-9137 is used to block HIV-1 integrase, critical for viral DNA integration into the host genome, advancing HIV research.
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