Dolutegravir sodium, soluble in DMSO and insoluble in ethanol and water, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread. It targets HIV integrase.
Dolutegravir sodium is utilized in research to inhibit HIV integrase, a key enzyme for the integration of viral DNA into the host genome, thus playing a crucial role in the treatment of HIV-1 infection.
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