GSK744, soluble in warmed DMSO and insoluble in water and ethanol, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread. It targets HIV integrase.
GSK744 is a long-acting HIV integrase inhibitor researched for preventing integration of viral DNA into the host genome, helping to impede HIV replication.
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