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Escherichia coli lipid A
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Cat. No.: X26-02-ZQ4715

Escherichia coli lipid A

Synonym: [(2R,3S,4R,5R,6R)-2-[[(2R,3R,4R,5S,6R)-3-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-6-(hydroxymethyl)-5-phosphonooxy-4-[(3R)-3-tetradecanoyloxytetradecanoyl]oxyoxan-2-yl]oxymethyl]-3-hydroxy-5-[[(3R)-3-hydroxytetradecanoyl]amino]-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxytetradecanoate

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Product Size
1 mg; 10 mg; 25 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
This hexa-acylated structure is considered the gold standard "canonical" Lipid A for inducing a robust inflammatory response. It is the primary tool used globally for calibrating endotoxin assays and studying innate immune signaling mechanisms.
Molecular Weight
1798.4
Molecular Formula
C94H178N2O25P2
Source
Chemical synthesis
Form
Solid or liquid
Purity
≥90%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Escherichia coli lipid A can be used as the definitive hexa-acylated standard for inducing high-potency TLR4-mediated immune activation.
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