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Cat. No.: X23-10-ZQ761

IKK/IκB inhibitor BAY 11-7085, Purity ≥98%

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Synonym: bay 11-7085; 196309-76-9; (E)-3-(4-tert-Butylphenylsulfonyl)acrylonitrile; (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile; BAY 11-7083; bay11-7085; (E)-3-(4-tert-Butylphenyl)sulfonylprop-2-enenitrile; IKK/IκB inhibitor

  • MDL: MFCD01862602
  • CAS Number: 196309-76-9
  • Compound CID: 5353432
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BAY 11-7085, soluble in DMSO and ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IκBα phosphorylation.
Molecular Weight
249.33
Molecular Formula
C13H15NO2S
Targets
IκBα phosphorylation: 10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 49 mg/mL (196.52 mM); Water: Insoluble; Ethanol: 49 mg/mL (196.52 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BAY 11-7085 can be used to investigate its effects on inhibiting NF-κB activation by blocking IκBα phosphorylation.
Publications
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