Properties
                                        
                            Description
                            IKK-16, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK complex, IKK1, and IKK2.
                         
                                                                            
                                                            
                            Molecular Formula
                            C28H29N5OS
                         
                                                                                                                                            
                            Targets
                            IKK complex: 70 nM; IKK1: 200 nM; IKK2: 40 nM
                         
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                            
                                                                                                                                                                            
                            Solubility
                            DMSO: 95 mg/mL (196.42 mM); Water: Insoluble; Ethanol: Insoluble
                         
                                                            
                            Identity
                            Confirmed by NMR/HPLC/MS.
                         
                                                                                                                                                            
                            Applications
                            IKK-16 can be studied for its specific inhibition of IKK-1 and IKK-2 in modulating the NF-κB signaling pathway.