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Cat. No.: X23-10-ZQ784

IKK/IκB inhibitor IKK epsilon-IN-1, Purity ≥98%

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Synonym: 1292310-49-6; IKK epsilon-IN-1; TBK1/IKK|A-IN-2; 5-(2-((4-Morpholinophenyl)amino)pyrimidin-4-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile; IKK(epsilon)-IN-1 (IKKE-IN-1); IKKepsilon-IN-1; 5-[2-(4-Morpholin-4-ylanilino)pyrimidin-4-yl]-2-(oxan-4-yloxy)benzonitrile; IKK/IκB inhibitor

  • MDL: MFCD28167836
  • CAS Number: 1292310-49-6
  • Compound CID: 51049969
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
IKK epsilon-IN-1, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKKε and TBK1.
Molecular Weight
457.52
Molecular Formula
C26H27N5O3
Targets
IKKε: 3.9 nM (At 10 μM ATP); TBK1: 0.6 nM (At 5 μM ATP)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 57 mg/mL (124.58 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IKK epsilon-IN-1 can be used to study its inhibitory effects on IKKε and its potential applications in inflammatory diseases.
Publications
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