IKK/IκB inhibitor LY2409881, Purity ≥98%

Synonym: 946518-60-1; LY2409881 trihydrochloride; LY2409881; LY2409881 (trihydrochloride); 2-(5-Chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide trihydrochloride; 2-(5-Chloro-2-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide trihydrochloride; IKK/IκB inhibitor

MDL: MFCD28900676
CAS Number: 946518-60-1
Compound CID: 68856073

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

LY2409881, soluble in warmed DMSO and insoluble in water and ethanol, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK2.

Molecular Weight

594.43

Molecular Formula

C₂₄H₃₂Cl₄N₆OS

Targets

IKK2: 30 nM

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 18 mg/mL (30.28 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

LY2409881 can be used to explore its role as an inhibitor of IKK2 in NF-κB signaling and its implications in cancer therapy.

Publications

Publications (0)

Publications

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