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IKK/IκB inhibitor PS-1145, Purity ≥98%
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Cat. No.: X23-10-ZQ764

IKK/IκB inhibitor PS-1145, Purity ≥98%

Synonym: PS-1145; 431898-65-6; PS 1145; IKK Inhibitor X; N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide; N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide; IKK/IκB inhibitor

  • MDL: MFCD18089825
  • CAS Number: 431898-65-6
  • Compound CID: 9949093
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
PS-1145, soluble in DMSO and warmed ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK.
Molecular Weight
322.75
Molecular Formula
C17H11ClN4O
Targets
IKK: 88 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 61 mg/mL (189 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (6.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PS-1145 can be used to explore its role as an IκB kinase inhibitor in regulating NF-κB signaling in various pathological conditions.
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