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IKK/IκB inhibitor SC-514, Purity ≥98%
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Cat. No.: X23-10-ZQ763

IKK/IκB inhibitor SC-514, Purity ≥98%

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Synonym: SC-514; 354812-17-2; 4-Amino-[2,3'-bithiophene]-5-carboxamide; Sc 514; SC514; 3-amino-5-thiophen-3-ylthiophene-2-carboxamide; 3-Amino-5-(3-thienyl)thiophene-2-carboxamide; IKK/IκB inhibitor

  • CAS Number: 354812-17-2
  • Compound CID: 2807869
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SC-514, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets AUR2, CDK2/CyclinA, cAbl, Chk1, EGFR, ERK2, FGFR1, GSK-3, IKK2, JNK1, and JNK2.
Molecular Weight
224.3
Molecular Formula
C9H8N2OS2
Targets
AUR2: 71 μM; CDK2/CyclinA: 61 μM; cAbl: >100 μM; Chk1: >100 μM; EGFR: >100 μM; ERK2: >100 μM; FGFR1: >100 μM; GSK-3: >100 μM; IKK2: 3-12 μM; JNK1: >200 μM; JNK2: >200 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 41 mg/mL (182.79 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SC-514 can be utilized to investigate its specific inhibitory effects on IKKβ in the NF-κB pathway in inflammation and cancer studies.
Publications
Publications (0)

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