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IKK/IκB inhibitor TPCA-1, Purity ≥98%
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Cat. No.: X23-10-ZQ759

IKK/IκB inhibitor TPCA-1, Purity ≥98%

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Synonym: TPCA-1; 507475-17-4; 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide; IKK-2 Inhibitor IV; TPCA1; 2-(Carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide; [5-(p-Fluorophenyl)-2-ureido]thiophene-3-carboxamide; IKK/IκB inhibitor

  • MDL: MFCD09037541
  • CAS Number: 507475-17-4
  • Compound CID: 9903786
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TPCA-1, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK2.
Molecular Weight
279.29
Molecular Formula
C12H10FN3O2S
Targets
IKK2: 17.9 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 49 mg/mL (175.44 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TPCA-1 can be used to explore its specific inhibitory effects on IKK-β in the NF-κB signaling pathway in inflammatory diseases and cancer research.
Publications
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