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Neisseria meningitidis lipid A
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Cat. No.: X26-02-ZQ4714

Neisseria meningitidis lipid A

Synonym: [(2R,3S,4R,5R,6R)-5-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-2-[[(2R,3R,4R,5S,6R)-3-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-4-[(3R)-3-hydroxydodecanoyl]oxy-6-(hydroxymethyl)-5-phosphonooxyoxan-2-yl]oxymethyl]-3-hydroxy-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxydodecanoate

  • CAS Number: 770734-61-7
  • Compound CID: 24774162
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Product Size
1 mg; 10 mg; 25 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
This potent endotoxin from the meningitis-causing bacterium is characterized by its high affinity for the human TLR4-MD2 complex. It is used in vaccine research and studies focusing on the rapid induction of the cytokine storm during bacterial sepsis.
Molecular Weight
1714.2
Molecular Formula
C88H166N2O25P2
Source
Chemical synthesis
Form
Solid or liquid
Purity
≥90%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Neisseria meningitidis lipid A can be used to study the contribution of the Lipid A structure to the virulence and meningeal inflammation caused by the pathogen.
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