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Integrin inhibitor, Lifitegrast, Purity ≥98%
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Cat. No.: X24-08-YM305

Integrin inhibitor, Lifitegrast, Purity ≥98%

Synonym: 1025967-78-5; SAR-1118; SAR 1118; SAR1118; Lifitegrast; brand name: Xiidra.; (2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid

  • MDL: MFCD28502439
  • CAS Number: 1025967-78-5
  • Compound CID: 11965427
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Product Size
10 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
MSDS
Properties
Description
Lifitegrast, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin.
Molecular Weight
615.478
Molecular Formula
C29H24Cl2N2O7S
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 98 mg/mL (159.22 mM); Water: insoluble; Ethanol: 20 mg/mL
Applications
Lifitegrast is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of dry eye disease by blocking the interaction of integrin αLβ2 with its ligand, which reduces inflammation and improves symptoms.
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