As one of the most well-characterized natural TLR4 antagonists, this lipid is frequently used to block endotoxin-induced cytokine production. It is essential for high-resolution studies of the MD-2 binding pocket and competitive ligand displacement.
Molecular Weight
1527.9
Molecular Formula
C76H140N2O24P2
Source
Chemical synthesis
Form
Solid or liquid
Purity
≥90%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Rhodobacter sphaeroides Lipid A can be used in immunological research as a potent antagonist of human TLR4-mediated cytokine production.
Publications
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Publications
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