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Cat. No.: X24-08-YM322
Kinesin inhibitor, ARQ 621, Purity ≥98%
Synonym: 1095253-39-6; BCP28395; VTB25339; NSC771644; N-(3-Aminopropyl)-N-[(1R)-1-(3-anilino-7-chloro-4-oxoquinazolin-2-yl)but-3-ynyl]-3-chloro-2-fluorobenzamide
- CAS Number: 1095253-39-6
- Compound CID: 25110841
Properties
Description
ARQ 621, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin.
Molecular Weight
552.43
Molecular Formula
C28H24Cl2FN5O2
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 89 mg/mL (161.1 mM); Water: insoluble; Ethanol: 89 mg/mL (161.1 mM)
Applications
ARQ 621 is a cytoskeletal signaling inhibitor that plays a key role in interfering with mitotic spindle formation, leading to cell cycle arrest and apoptosis in tumor cells.
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