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Kinesin inhibitor, SB 743921, Purity ≥98%
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Cat. No.: X24-08-YM317

Kinesin inhibitor, SB 743921, Purity ≥98%

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Synonym: 940929-33-9; SB-743921; SB743921; SB-743921 hydrochloride; N-(3-Aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide; hydrochloride

  • CAS Number: 940929-33-9
  • Compound CID: 49867937
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SB 743921, soluble in DMSO, water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the KSP, KSP(Colo205cells), KSP(MV522cells), and KSP(MX1cells).
Molecular Weight
553.5
Molecular Formula
C31H33N2O3·HCl
Targets
KSP: 0.1nM; KSP (Colo205cells): 0.07nM; KSP (MV522cells): 1.7nM; KSP (MX1cells): 0.06nM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 103 mg/mL (186.08 mM); Water: 20 mg/mL (36.13 mM); Ethanol: 103 mg/mL (186.08 mM); In vivo: Saline pH 5.0, 28 mg/mL
Applications
SB 743921 is a cytoskeletal signaling inhibitor that displays the significant potential to act as an effective anti-cancer agent due to its role in disrupting cell division and reducing tumor growth.
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