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Kinesin inhibitor, Ispinesib, Purity ≥98%
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Cat. No.: X24-08-YM316

Kinesin inhibitor, Ispinesib, Purity ≥98%

Synonym: 336113-53-2; Ispinesib mesylate; B-715992; CK 0238273; N-(3-Aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxoquinazolin-2-yl)-2-methylpropyl]-4-methylbenzamide

  • CAS Number: 336113-53-2
  • Compound CID: 6851740
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
Ispinesib, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the KSP (HsEg5) (cell-free assay).
Molecular Weight
517.1
Molecular Formula
C30H33ClN4O2
Targets
KSP (HsEg5) (Cell-free assay): 1.7 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 93 mg/mL (179.86 mM); Water: insoluble; Ethanol: 93 mg/mL (179.86 mM)
Applications
Ispinesib is a cytoskeletal signaling inhibitor that can be used for its ability to disrupt mitotic spindle formation, leading to cancer cell death.
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