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Kinesin inhibitor, BAY1217389, Purity ≥98%
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Cat. No.: X24-08-YM334

Kinesin inhibitor, BAY1217389, Purity ≥98%

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Synonym: 1554458-53-5; BAY 1217389; BAY-1217389; N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-(3,3,3-trifluoropropylamino)imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

  • MDL: MFCD30502614
  • CAS Number: 1554458-53-5
  • Compound CID: 78320750
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Product Size
2 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BAY1217389, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Mps1.
Molecular Weight
561.5
Molecular Formula
C27H24F5N5O3
Targets
Mps1: 0.63 nM (IC50)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 92 mg/mL (163.84 mM); Water: insoluble; Ethanol (warmed): 3 mg/mL (5.34 mM)
Applications
BAY1217389 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancer by disrupting mitotic spindle formation, leading to cell cycle arrest and increased cancer cell death.
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